Plankton

Sheldon James Plankton''' is Mr. Krabs' nemesis and the antagonist in the SpongeBob SquarePants series. He operates a struggling restaurant called the Chum Bucket, located directly across the street from the Krusty Krab. His primary goal in the series is to steal the Patty Krabby Patty recipe and put Mr. Krabs out of business. Plankton succeeds at stealing the recipe in the movie, but his goal of world domination is thwarted by SpongeBob. In "Friend or Foe," it was revealed that Mr. Krabs and Plankton were once best friends, but a dispute over the Krabby Patty recipe ended their friendship.

Nicktoons Unite!
In Nicktoons Unite! Plankton serves as one of the four major antagonist of the game. With the power of the strongest villains in the universe, Plankton is able to take control of Bikini Bottom and uses multiple tank-like vacuums to suck away all of the cities civilians. Plankton captures Mr. Krabs and numerous Jellyfish, extracting there power from their sting. Plankton is eventually defeated in a brawl on top of the Chum Bucket (modified to look like a grand castle).